Regulation of DNA replication initiation in human cells

In order to divide,each cell needs to duplicate its DNA first. It is a complex process that is initiated at thousands different sites in a very well orchestrated fashion. We are studying how it is controlled and which proteins participate in this process.

News.

Oct 24, 2024

Very happy to visit our colleagues at Eppley Cancer Institute in Omaha, NE, and present our latest research! Thank you very much Dr. Youri Pavlov for the invitation!

Sep 16, 2024

We welcome PhD students Jorlane de Jesus and Kyle Yuncza for their first rotation in our lab this semester! Good luck!

Aug 31, 2024

PhD student Raviteja Chavata presented his work on DNA polymerase epsilon at the 7th DNA Polymerases Meeting in Warsaw, Poland!

Jun 05, 2024

Congratulations Artur Morgunov on successfully defending his Bachelor's thesis with the highest score and being recognized for the best thesis in his group! Best of luck in your future!

May 06, 2024

The first postdoctoral associate Gregory Zamalloa joins the Pittsburgh lab! Welcome, Greg!

Feb 12, 2024

TM lab at the UPMC Hillman Cancer Center/University of Pittsburgh is now open!

Jan 25, 2024

Congratulations Karina Šapovalovaitė on successfully defending her Master's thesis with the highest score! Best of luck in your future!

Sep 01, 2023

Bachelor's student Evelina Koop joins the lab! Welcome, Evelina!

Jul 30, 2023

Sameera's review on TIMELESS' enormous array of functions in now published in JMB! Check it out!

Jun 07, 2023

Congratulations Pille Leesmäe on successfully defending her Bachelor's thesis with the highest score! Best of luck in your future!

Mar 03, 2023

Bachelor's student Arthur Morgunov joins the lab! Welcome, Arthur!

Feb 03, 2023

Our work is covered by Estonian media! Check it out here (in Estonian) or here (in Russian) or here (in English)

Nov 19, 2022

The first paper from the lab is now published in Nature communications! Check it out!

Nov 15, 2022

PhD student Naga Raviteja Chavata joins the lab! Welcome, Ravi!

Sep 20, 2022

A collaborative paper with our participarion is now out in Cell reports!

Sep 01, 2022

Master's student Marleen Mikk joins the lab! Welcome, Marleen!

Jun 08, 2022

Congratulations Sigvard Vällo on successfully defending his Bachelor's thesis with the highest score! Best of luck in your future!

May 25, 2022

Happy to present our work at the 6th DNA Polymerases Meeting in Stockholm!

Apr 08, 2022

PhD student Syed Shahid Musvi joins the lab! Welcome, Shahid!

Mar 22, 2022

First preprint from the lab! We use an auxin-inducible degron system to study the non-catalytic role of DNA polymerase epsilon in human cells.

Feb 28, 2022

Very excited to have contributed to this new preprint on the effects of ATRi on proliferating T-cells! Check it out!

Feb 21, 2022

Bachelor's student Pille Leesmäe joins the lab! Welcome, Pille!

Jan 18, 2022

Congratulations Hele Anderspuk on successfully defending her Master's thesis with the highest score! Best of luck in your future!

Dec 07, 2021

Amazing news: our lab was awarded a team grant from Estonian Research Council for 2022-2026!

Nov 26, 2021

Very excited to give an invited talk about our research at the University of Tartu Institute of Technology!

Sep 10, 2021

Come see our poster about DNA polymerase epsilon at CSHL DNA replication meeting!

Mar 23, 2021

PhD student Sameera Vipat joins the lab! Welcome, Sameera!

Nov 20, 2020

We have an open PhD student position! Come join us at TalTech!

Apply here before December 16th 2020.

Sep 11, 2020

Bachelor's student Sigvard Vällo joins the lab! Welcome, Sigvard!

Jun 29, 2020

We are back!

Mar 16, 2020

We are on quarantine. Stay safe!

Nov 23, 2019

Our paper is published in PNAS!

Nov 20, 2019

Master's student Hele Anderspuk joins the lab! Welcome, Hele!

Aug 01, 2019

The lab is now open!